Classification of Thymus-derived and Marrow-derived Lymphocytes by Demonstration of Their Antigen-binding Characteristics
نویسندگان
چکیده
Antigen-binding cells of T and B origin can readily be determined by quantitating the number of sheep erythrocytes per rosette after glutaraldehyde fixation. The T(1) and T(2) populations have low antigen-binding properties and are very unstable without fixation. The B(1) and B(2) populations are stable and correlate with precursor and secretory cells. Fixation of rosettes permits a sensitive test for studying differentiation of T and B cells.
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 135 شماره
صفحات -
تاریخ انتشار 1972